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The Buzz | Jan/Feb '19

The Buzz

TO READ | Basic Research, Deep Controversy

Dieter Egli, PhD, a developmental biologist at Columbia University, is conducting experiments designed to modify DNA in human embryos as a step toward someday preventing inherited diseases, NPR reports. He is currently trying to fix one of the genetic defects that cause retinitis pigmentosa.

TO LISTEN | The Dropout

Stanford-dropout-turned-tech-entrepreneur Elizabeth Holmes wowed Silicon Valley with a finger-pricking blood test that could revolutionize diagnostic testing. Only problem? It didn’t actually work. The Dropout (ABC Radio and ABC News Nightline) chronicles the rise and fall of this master manipulator and gives voice to the many investors, researchers, and patients she deceived. Listen in.

TO SKIMM | JAMA’s Most-Talked-About Articles of 2018

1. Effect of Low-Fat vs Low-Carbohydrate Diet on 12-Month Weight Loss in Overweight Adults and the Association With Genotype Pattern or Insulin Secretion: The DIETFITS Randomized Clinical Trial

2. Health Care Spending in the United States and Other High-Income Countries

3. Effect of Opioid vs Nonopioid Medications on Pain-Related Function in Patients With Chronic Back Pain or Hip or Knee Osteoarthritis Pain: The SPACE Randomized Clinical Trial

4. Neurological Manifestations Among US Government Personnel Reporting Directional Audible and Sensory Phenomena in Havana, Cuba

5. The Proposal to Lower P Value Thresholds to .005

6. Vitamin and Mineral Supplements: What Clinicians Need to Know

7. The Physical Activity Guidelines for Americans

8. Prevalence of Prescription Medications With Depression as a Potential Adverse Effect Among Adults in the United States

9. The Challenge of Reforming Nutritional Epidemiologic Research

10. Association of Digital Media Use With Subsequent Symptoms of Attention-Deficit/Hyperactivity Disorder Among Adolescents

TO FOLLOW | @EyeRounds

For scroll-stopping clinical images and interactive case discussions, follow the University of Iowa Ophthalmology & Visual Sciences account @EyeRounds.

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